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Passive Avoidance - Step through - New Model

The Passive Avoidance Set-Up (step-trough method) by Ugo Basile, is an efficient and reliable insturument fo the classic Passive Avoidance Test.
Key Benefits
The Passive Avoidance Set-Up (step-trough method) by Ugo Basile, is an efficient and reliable insturument fo the classic Passive Avoidance Test. 
Multiple configurations can be controlled by the NEW  electronic with touch-screen, which encompsses a precision 8-pole shocker.
The P.A. set-up is part of UB conditioning-cage project; you buy a single touch-screen controller, and manage all UB cages. Ask for details!
Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid, and an aversive stimulus, represented by a mild foot shock. The tests are conducted in a two-compartment apparatus, where one is dimly lit and preferable to a rodent, and the other is brightly lit.
Ugo Basile Passive Avoidance set-up instrument basically consists of a Controller, and a Cage divided into two compartments by a partition which embodies a sliding door.
The tilting floor ensures a simple and relaible detection mechanism to score the animal’s movement across the two compartments.The 40500-001 Programming/Recording Unit, encompasses all controls, incorporates a constant-current high precision 8-pole shocker, and manages data acquisition: data are stored insite the unit and can be downloaded via the USB key provided as standard, for further processing via Excel, Access, etc.
The Unit, which incorporates a 12” touch-screen, manages both Passive and Active Avoidance Tests. Up to 4 cages can be connected to the same Controller. If more than one cage is connected, an expansion box 40500-005 is required for each additional cage. 
Remote Control feature will make remote service and software upgrades extremely simple!
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  • Part of the BEEHIVE SYSTEM
  • Tilt-floor detection mechanism
  • No stepping motor! 
  • Remote Control feature 
  • Great Versatility 
  • the electronic unit encompasses all controls for up to 4 animal cages!
  • Reliable and precise detection of animal crossing
  • Silent and automated sliding door to divide the two compartments
  • Makes remote service and software upgrades extremely simple!
  • The same controller can manage different conditioning tests. Ask for details! 
  • C.I. Navarro-Francés et alia: “Influence of trait anxiety on the effects of acute stress on learning and retention of the passive avoidance task in male and female mice” Behav. Processes 105: 6-14, 2014
  • L. Zvejniece et alia: “The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors” Br. J. Pharmacol. 171(3): 761-771, 2014
  • P. Borracci et alia: “Rat embryo exposure to all-trans retinoic acid results in long-term cognitive deficits” Eur. Rev. Med. Pharmacol. Sci 18:28-33, 2014
  • C. Nasuti et alia: “Neonatal exposure to permethrin pesticide causes lifelong fear and spatial learning deficits and alters hippocampal morphology of synapses” J. Neurodevelopmental Disorders 6-7: 1866-1955, 2014
  • R.W. Flint et alia: “NMDA Receptor Antagonism with MK-801 Impairs Consolidation and Reconsolidation of Passive Avoidance Conditioning in Adolescent Rats: Evidence for a State Dependent Reconsolidation Effect” Neurobiology of Learning and Memory 101: 114-119, 2013
  • G. Telegdy et alia: “The Action of Kisspeptin-13 on Passive Avoidance Learning in Mice. Involvement of Transmitters” Behav. Brain Res. 243: 300-305, 2013
  • V. Capurro et alia: “Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer’s Disease” PLoS ONE 8(2): e56870, 2013
  • J. Michaud et alia: “Hematopoietic MyD88-Adaptor Pro­tein Acts as a Natural Defense Mechanism for Cognitive Deficits in Alzheimer’s Disease” Stem Cell Reviews and Reports 8 (3): 898-904, 2012
  • E.R.A.Y. Detrait et alia: “The inhibitory avoidance test op­timized for discovery of cognitive enhancers” Behavior Research Methods 41 (3): 805-811, 2009 
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